Reactome | p-EPHs bind VAV2,3

Schema > Reaction > Entries

p-EPHs bind VAV2,3 Show undefined attributes

category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10172241
displayName	p-EPHs bind VAV2,3
eventOf	[Pathway:R-RNO-3928665] EPH-ephrin mediated repulsion of cells - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-3928604] SFKs phosphorylate VAV2,3 - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-3928607] p-EPHs bind VAV2,3 - Homo sapiens
input	[Complex:R-RNO-3928499] p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] [DefinedSet:R-RNO-2424458] VAV2,VAV3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	p-EPHs bind VAV2,3
output	[Complex:R-RNO-3928540] EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-3928607
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-3928665] EPH-ephrin mediated repulsion of cells
(precedingEvent)	[Reaction:R-RNO-3928604] SFKs phosphorylate VAV2,3
(inferredTo)	[Reaction:R-HSA-3928607] p-EPHs bind VAV2,3