Reactome | p-EPHs bind VAV2,3

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p-EPHs bind VAV2,3 Show undefined attributes

authored	[InstanceEdit:3928653] Garapati, P V, 2013-07-22
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:3928638] Garapati, P V, 2013-07-22
dbId	3928607
displayName	p-EPHs bind VAV2,3
edited	[InstanceEdit:3928653] Garapati, P V, 2013-07-22
eventOf	[Pathway:R-HSA-3928665] EPH-ephrin mediated repulsion of cells - Homo sapiens
followingEvent	[Reaction:R-HSA-3928604] SFKs phosphorylate VAV2,3 - Homo sapiens
input	[Complex:R-HSA-3928499] p-EPH:ephrin oligomers:SRC,FYN,YES1,LYN [plasma membrane] [DefinedSet:R-HSA-2424458] VAV2,VAV3 [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3928129] Vav family GEFs link activated Ephs to endocytosis and axon guidance
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	p-EPHs bind VAV2,3
orthologousEvent	[Reaction:R-CEL-3928607] p-EPHs bind VAV2,3 - Caenorhabditis elegans [Reaction:R-GGA-3928607] p-EPHs bind VAV2,3 - Gallus gallus [Reaction:R-XTR-3928607] p-EPHs bind VAV2,3 - Xenopus tropicalis [Reaction:R-SSC-3928607] p-EPHs bind VAV2,3 - Sus scrofa [Reaction:R-BTA-3928607] p-EPHs bind VAV2,3 - Bos taurus [Reaction:R-CFA-3928607] p-EPHs bind VAV2,3 - Canis familiaris [Reaction:R-RNO-3928607] p-EPHs bind VAV2,3 - Rattus norvegicus [Reaction:R-MMU-3928607] p-EPHs bind VAV2,3 - Mus musculus
output	[Complex:R-HSA-3928540] EFNAs/EFNBs:p-EPHAs/p-EPHBs:SFKs:VAV2,VAV3 [plasma membrane]
releaseDate	2014-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5490284] Ip, Nancy Y, 2014-05-19
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-3928607
summation	[Summation:3928302] The alternate method required for the initial EPH receptor:e...

Referrals

(precedingEvent)	[Reaction:R-HSA-3928604] SFKs phosphorylate VAV2,3
(hasEvent)	[Pathway:R-HSA-3928665] EPH-ephrin mediated repulsion of cells

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