Reactome | SFTPA oligomer, SFTPD oligomer [extracellular region]

Schema > DefinedSet > Entries

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-RNO-391109] SIRPA:SFTPA oligomer, SFTPD oligomer [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5432814] SFTPA/SFTPD binds TLR2:TLR1 - Rattus norvegicus [Reaction:R-RNO-391155] SIRPA binds SFTPA oligomer, SFTPD oligomer - Rattus norvegicus [Reaction:R-RNO-5432852] SFTPA/SFTPD binds TLR4:LY96 - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10116845
displayName	SFTPA oligomer, SFTPD oligomer [extracellular region]
hasMember	[Polymer:R-RNO-391092] SFTPA oligomer [extracellular region] - Rattus norvegicus [Polymer:R-RNO-391097] SFTPD oligomer [extracellular region] - Rattus norvegicus
inDisease	false
inferredFrom	[DefinedSet:R-HSA-391108] SFTPA oligomer, SFTPD oligomer [extracellular region] - Homo sapiens
maxDepth	4
name	SFTPA oligomer, SFTPD oligomer
negativelyRegulates	[NegativeRegulation:10116849] Negative regulation by 'SFTPA oligomer, SFTPD oligomer [extracellular region]'
schemaClass	DefinedSet
species	[Species:48895] Rattus norvegicus
stId	R-RNO-391108

(input)	[Reaction:R-RNO-391155] SIRPA binds SFTPA oligomer, SFTPD oligomer [Reaction:R-RNO-5432852] SFTPA/SFTPD binds TLR4:LY96 [Reaction:R-RNO-5432814] SFTPA/SFTPD binds TLR2:TLR1
(hasComponent)	[Complex:R-RNO-391109] SIRPA:SFTPA oligomer, SFTPD oligomer [plasma membrane] [Complex:R-RNO-5432881] SP-A/SP-D:TLR4:MD2 [plasma membrane] [Complex:R-RNO-5432872] SFTPA/SFTPD:TLR2:TLR1 [plasma membrane]
(regulator)	[NegativeRegulation:10116849] Negative regulation by 'SFTPA oligomer, SFTPD oligomer [extracellular region]'
(inferredTo)	[DefinedSet:R-HSA-391108] SFTPA oligomer, SFTPD oligomer [extracellular region]