Reactome | SUMOylation of transcription cofactors

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SUMOylation of transcription cofactors Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10224521
displayName	SUMOylation of transcription cofactors
eventOf	[Pathway:R-RNO-3108232] SUMO E3 ligases SUMOylate target proteins - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-RNO-5228521] PIAS1,4 SUMOylate CASP8AP2 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-3927824] PRC1 SUMOylates CASP8AP2 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-3108209] PRC1 SUMOylates CTBP1 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-3108203] PRC1 SUMOylates CTBP1 with SUMO2,3 - Rattus norvegicus [Reaction:R-RNO-4085992] SUMOylation of DAXX with SUMO1 - Rattus norvegicus [Reaction:R-RNO-3900177] SUMOylation of DDX5 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-3900194] PIAS1 SUMOylates DDX5 with SUMO2 - Rattus norvegicus [Reaction:R-RNO-3900047] SUMOylation of DDX17 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-3899291] SUMOylation of EP300 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-4086083] SUMOylation of ING2 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-4090288] PIAS1,3 SUMOylate MBD1 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-3900070] SUMOylation of MKL1 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-4085296] SUMOylation of NCOA1 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-4086088] SUMOylation of NPM1 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-4086059] SUMOylation of NPM1 with SUMO2,3 - Rattus norvegicus [Reaction:R-RNO-4086036] PIAS1,3 SUMOylate NRIP1 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-4085331] PIAS2-1 SUMOylates PARK7 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-4085347] PIAS1 SUMOylates SAFB with SUMO1 - Rattus norvegicus [Reaction:R-RNO-4085372] PIAS1 SUMOylates SAFB with SUMO2,3 - Rattus norvegicus [Reaction:R-RNO-4085994] TOPORS SUMOylates SIN3A with SUMO1 - Rattus norvegicus [Reaction:R-RNO-3782535] TRIM28 SUMOylates TRIM28:ZNF350 with SUMO1 - Rattus norvegicus [Reaction:R-RNO-3296126] CBX4, UHRF2 SUMOylate ZNF131 with SUMO1 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-3899300] SUMOylation of transcription cofactors - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	SUMOylation of transcription cofactors
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-3899300
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-3108232] SUMO E3 ligases SUMOylate target proteins
(inferredTo)	[Pathway:R-HSA-3899300] SUMOylation of transcription cofactors

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