Reactome | Alpha-oxidation of phytanate

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Alpha-oxidation of phytanate Show undefined attributes

compartment	[Compartment:17951] peroxisomal matrix
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10223633
displayName	Alpha-oxidation of phytanate
eventOf	[Pathway:R-RNO-390918] Peroxisomal lipid metabolism - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:26178] fatty acid alpha-oxidation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-389622] phytanate + CoA-SH + ATP => phytanoyl-CoA + AMP + pyrophosphate - Rattus norvegicus [Reaction:R-RNO-6809810] PECR reduces 2E-phytenoyl-CoA to phytanoyl-CoA - Rattus norvegicus [Reaction:R-RNO-389639] phytanoyl-CoA + 2-oxoglutarate + O2 => 2-hydroxyphytanoyl-CoA + succinate + CO2 - Rattus norvegicus [Reaction:R-RNO-389611] 2-hydroxyphytanoyl-CoA => pristanal + formyl-CoA - Rattus norvegicus [Reaction:R-RNO-389609] ALDH3A2-2 oxidizes pristanal to pristanate - Rattus norvegicus [Reaction:R-RNO-389632] pristanate + CoA-SH + ATP => pristanoyl-CoA + AMP + pyrophosphate - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-389599] Alpha-oxidation of phytanate - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Alpha-oxidation of phytanate
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-389599
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-390918] Peroxisomal lipid metabolism
(inferredTo)	[Pathway:R-HSA-389599] Alpha-oxidation of phytanate