Reactome | WNT signaling stimulates CSNK1-dependent phosphorylation of DVL

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WNT signaling stimulates CSNK1-dependent phosphorylation of DVL Show undefined attributes

catalystActivity	[CatalystActivity:10171550] protein serine/threonine kinase activity of CSNK1E [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10171552
displayName	WNT signaling stimulates CSNK1-dependent phosphorylation of DVL
eventOf	[Pathway:R-RNO-201688] WNT mediated activation of DVL - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-3772434] Phosphorylated DVL recruits PIP5K1B to the plasma membrane - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-3772435] WNT signaling stimulates CSNK1-dependent phosphorylation of DVL - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [DefinedSet:R-RNO-201689] p-DVL [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	WNT signaling stimulates CSNK1-dependent phosphorylation of DVL
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [DefinedSet:R-RNO-3772407] pp-DVL [cytosol]
precedingEvent	[Reaction:R-RNO-201717] CSNK2-mediated phosphorylation of DVL - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-3772435
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-201688] WNT mediated activation of DVL
(precedingEvent)	[Reaction:R-RNO-3772434] Phosphorylated DVL recruits PIP5K1B to the plasma membrane
(inferredTo)	[Reaction:R-HSA-3772435] WNT signaling stimulates CSNK1-dependent phosphorylation of DVL

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