Reactome | CX3CR1 binds CX3CL1

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10130342
displayName	CX3CR1 binds CX3CL1
eventOf	[Pathway:R-RNO-380108] Chemokine receptors bind chemokines - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-373342] CX3CR1 binds CX3CL1 - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-373368] Cx3cl1 [extracellular region] [EntityWithAccessionedSequence:R-RNO-2980688] Cx3cr1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CX3CR1 binds CX3CL1
output	[Complex:R-RNO-373352] CX3CR1:CX3CL1 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-373342
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-380108] Chemokine receptors bind chemokines
(inferredTo)	[Reaction:R-HSA-373342] CX3CR1 binds CX3CL1