Reactome | Caspase mediated cleavage of BAP31

Schema > Reaction > Entries

Caspase mediated cleavage of BAP31 Show undefined attributes

catalystActivity	[CatalystActivity:10129779] cysteine-type endopeptidase activity of active caspase-8 [mitochondrial outer membrane]
category	transition
compartment	[Compartment:12045] endoplasmic reticulum membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10129781
displayName	Caspase mediated cleavage of BAP31
eventOf	[Pathway:R-RNO-111465] Apoptotic cleavage of cellular proteins - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-351948] Mitochondrial recruitment of Drp1 - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-351894] Caspase mediated cleavage of BAP31 - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-201587] Bcap31 [endoplasmic reticulum membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Caspase mediated cleavage of BAP31
output	[EntityWithAccessionedSequence:R-RNO-351912] Bcap31 [cytosol] [EntityWithAccessionedSequence:R-RNO-351826] Bcap31 [endoplasmic reticulum membrane] [EntityWithAccessionedSequence:R-RNO-351909] Bcap31 [endoplasmic reticulum membrane]
precedingEvent	[Reaction:R-RNO-351863] Translocation of active caspase-8 to the mitochondrial membrane - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-351894
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(precedingEvent)	[Reaction:R-RNO-351948] Mitochondrial recruitment of Drp1
(hasEvent)	[Pathway:R-RNO-111465] Apoptotic cleavage of cellular proteins
(inferredTo)	[Reaction:R-HSA-351894] Caspase mediated cleavage of BAP31