Reactome | Calcium Influx through Voltage-gated Calcium Channels

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Calcium Influx through Voltage-gated Calcium Channels Show undefined attributes

catalystActivity	[CatalystActivity:10129253] voltage-gated calcium channel activity of Voltage-gated Calcium Channels (pancreatic beta cell) [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10129255
displayName	Calcium Influx through Voltage-gated Calcium Channels
eventOf	[Pathway:R-RNO-422356] Regulation of insulin secretion - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-265645] Calcium Influx through Voltage-gated Calcium Channels - Homo sapiens
input	[SimpleEntity:R-ALL-74112] Ca2+ [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Calcium Influx through Voltage-gated Calcium Channels
output	[SimpleEntity:R-ALL-74016] Ca2+ [cytosol]
precedingEvent	[Reaction:R-RNO-265682] KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel - Rattus norvegicus [BlackBoxEvent:R-RNO-381713] Potassium voltage-gated channels close in reponse to PKA - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-265645
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-422356] Regulation of insulin secretion
(inferredTo)	[Reaction:R-HSA-265645] Calcium Influx through Voltage-gated Calcium Channels

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