Reactome | atRAL is reduced to atROL

Schema > Reaction > Entries

atRAL is reduced to atROL Show undefined attributes

catalystActivity	[CatalystActivity:10166818] all-trans-retinol dehydrogenase (NADP+) activity of DHRS3 [photoreceptor outer segment membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:74000] photoreceptor outer segment membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10166820
displayName	atRAL is reduced to atROL
eventOf	[Pathway:R-RNO-2187335] The retinoid cycle in cones (daylight vision) - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-RNO-2465938] RBP3 regulates atROL taken up by Muller cells - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-2465940] atRAL is reduced to atROL - Homo sapiens
input	[SimpleEntity:R-ALL-975622] atRAL [cytosol] [SimpleEntity:R-ALL-70106] H+ [cytosol] [SimpleEntity:R-ALL-29364] NADPH [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	atRAL is reduced to atROL
output	[SimpleEntity:R-ALL-2473607] atROL [cytosol] [SimpleEntity:R-ALL-29366] NADP+ [cytosol]
precedingEvent	[Reaction:R-RNO-2466085] at-retinyl is hydrolysed from R* to release atRAL - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2465940
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-2187335] The retinoid cycle in cones (daylight vision)
(precedingEvent)	[BlackBoxEvent:R-RNO-2465938] RBP3 regulates atROL taken up by Muller cells
(inferredTo)	[Reaction:R-HSA-2465940] atRAL is reduced to atROL