Reactome | The retinoid cycle in cones (daylight vision)

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The retinoid cycle in cones (daylight vision) Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10224447
displayName	The retinoid cycle in cones (daylight vision)
eventOf	[Pathway:R-RNO-2187338] Visual phototransduction - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:26144] retinoid metabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[BlackBoxEvent:R-RNO-2465938] RBP3 regulates atROL taken up by Muller cells - Rattus norvegicus [Reaction:R-RNO-2465971] RLBP1 binds atROL to form RLBP1:atROL - Rattus norvegicus [Reaction:R-RNO-2465919] AWAT2 transfers PALM to 11cROL forming 11cRPALM - Rattus norvegicus [BlackBoxEvent:R-RNO-2465934] 11cROL translocates from Muller cells to cone photoreceptor cells - Rattus norvegicus [Reaction:R-RNO-9656891] OPN1SW binds 11cRAL - Rattus norvegicus [Reaction:R-RNO-9656893] OPN1MW binds 11cRAL - Rattus norvegicus [Reaction:R-RNO-2465924] OPN1LW binds 11cRAL - Rattus norvegicus [Reaction:R-RNO-2465917] Photons induce isomerisation of 11c-retinyl to at-retinyl - Rattus norvegicus [Reaction:R-RNO-2466085] at-retinyl is hydrolysed from R* to release atRAL - Rattus norvegicus [Reaction:R-RNO-2465940] atRAL is reduced to atROL - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-2187335] The retinoid cycle in cones (daylight vision) - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	The retinoid cycle in cones (daylight vision)
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2187335
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-2187338] Visual phototransduction
(inferredTo)	[Pathway:R-HSA-2187335] The retinoid cycle in cones (daylight vision)

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