Reactome | p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-RNO-2424487] Phosphorylation of PLC-gamma by p-BTK/p-SYK - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10166548
displayName	p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane]
hasComponent	[Complex:R-RNO-2424460] p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] [EntityWithAccessionedSequence:R-RNO-2424454] phospho-p-Y223,Y551-BTK [cytosol] [SimpleEntity:R-ALL-179838] PI(3,4,5)P3 [plasma membrane] [DefinedSet:R-RNO-2424458] VAV2,VAV3 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-2424457] p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane] - Homo sapiens
maxDepth	6
memberOf	[DefinedSet:R-RNO-2424473] p-SYK/p-BTK [plasma membrane] - Rattus norvegicus
name	p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK
producedByEvent	[Reaction:R-RNO-2424484] Phosphorylation of BTK by p-SYK - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2424457
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-2424487] Phosphorylation of PLC-gamma by p-BTK/p-SYK
(hasMember)	[DefinedSet:R-RNO-2424473] p-SYK/p-BTK [plasma membrane]
(output)	[Reaction:R-RNO-2424484] Phosphorylation of BTK by p-SYK
(inferredTo)	[Complex:R-HSA-2424457] p-5Y-LAT:GRB2:SOS1:GADS:p-3Y-SLP-76:PLCG:VAV:p-Y223,Y551-BTK [plasma membrane]

Cite Us!