Reactome | Interaction of SIGLEC14/15/16 and DAP12

Schema > Reaction > Entries

category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10165006
displayName	Interaction of SIGLEC14/15/16 and DAP12
eventOf	[Pathway:R-RNO-2172127] DAP12 interactions - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-2172123] Interaction of SIGLEC14/15/16 and DAP12 - Homo sapiens
input	[Complex:R-RNO-548940] DAP12 dimer [plasma membrane] [DefinedSet:R-RNO-2326839] SIGLEC14/15/16 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Interaction of SIGLEC14/15/16 and DAP12
output	[Complex:R-RNO-2326835] SIGLEC14/15/16:DAP12 dimer [plasma membrane]
precedingEvent	[Reaction:R-RNO-2130151] Dimerization of DAP12 - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2172123
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-RNO-2172127] DAP12 interactions
(inferredTo)	[Reaction:R-HSA-2172123] Interaction of SIGLEC14/15/16 and DAP12

Cite Us!