Reactome | discoidal HDL [extracellular region]

candidateOf	[CandidateSet:R-RNO-9707486] LDL,HDL [extracellular region] - Rattus norvegicus
compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-RNO-266083] discoidal HDL:cholesterol [extracellular region] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-266089] Discoidal HDL binds membrane-associated free cholesterol - Rattus norvegicus [Reaction:R-RNO-264678] LCAT + discoidal HDL <=> LCAT:discoidal HDL complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10128867
displayName	discoidal HDL [extracellular region]
hasComponent	2 × [EntityWithAccessionedSequence:R-RNO-174720] Apoa1 [extracellular region] 10 × [SimpleEntity:R-ALL-171149] CHOL [extracellular region] 25 × [SimpleEntity:R-ALL-171066] PL [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-216752] discoidal HDL [extracellular region] - Homo sapiens
maxDepth	2
name	discoidal HDL
producedByEvent	[Reaction:R-RNO-349657] pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle - Rattus norvegicus [Reaction:R-RNO-216756] Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle - Rattus norvegicus [Reaction:R-RNO-264689] LCAT:discoidal HDL complex <=> LCAT + discoidal HDL - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-216752
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-266089] Discoidal HDL binds membrane-associated free cholesterol [Reaction:R-RNO-264678] LCAT + discoidal HDL <=> LCAT:discoidal HDL complex
(hasComponent)	[Complex:R-RNO-266083] discoidal HDL:cholesterol [extracellular region] [Complex:R-RNO-264684] LCAT:discoidal HDL complex [extracellular region]
(output)	[Reaction:R-RNO-264689] LCAT:discoidal HDL complex <=> LCAT + discoidal HDL [Reaction:R-RNO-349657] pre-beta HDL binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle [Reaction:R-RNO-216756] Apolipoprotein A-I binds membrane-associated cholesterol and phospholipid to form a discoidal HDL particle
(inferredTo)	[Complex:R-HSA-216752] discoidal HDL [extracellular region]
(hasCandidate)	[CandidateSet:R-RNO-9707486] LDL,HDL [extracellular region]

discoidal HDL [extracellular region] Show undefined attributes

Referrals