Reactome | Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-2160934] Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-2160935] SMURF1 ubiquitinates RHOA - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10164257
displayName	Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-RNO-975972] Smurf1 [cytosol] [Complex:R-RNO-2134534] Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction]
inDisease	false
inferredFrom	[Complex:R-HSA-2160929] Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] - Homo sapiens
maxDepth	5
name	Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1
producedByEvent	[Reaction:R-RNO-2160932] SMURF1 binds phosphorylated PARD6A - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2160929
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-2160935] SMURF1 ubiquitinates RHOA
(output)	[Reaction:R-RNO-2160932] SMURF1 binds phosphorylated PARD6A
(hasComponent)	[Complex:R-RNO-2160934] Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction]
(inferredTo)	[Complex:R-HSA-2160929] Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane]

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