Reactome | Hyaluronan metabolism

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Hyaluronan metabolism Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10224389
displayName	Hyaluronan metabolism
eventOf	[Pathway:R-RNO-1630316] Glycosaminoglycan metabolism - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:21627] hyaluronan metabolic process
hasDiagram	true
hasEHLD	false
hasEvent	[Polymerisation:R-RNO-2160851] HAS1,2,3 mediate the polymerization and export of HA - Rattus norvegicus [Pathway:R-RNO-2160916] Hyaluronan degradation - Rattus norvegicus [Reaction:R-RNO-2160915] Receptor-mediated uptake of HA - Rattus norvegicus [Reaction:R-RNO-2142859] Growing HA is extruded from the cell by ABCC5 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-2142845] Hyaluronan metabolism - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	3
name	Hyaluronan metabolism
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2142845
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1630316] Glycosaminoglycan metabolism
(inferredTo)	[Pathway:R-HSA-2142845] Hyaluronan metabolism

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