Reactome | Translocation of TGN-lysosome vesicle to lysosome

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Translocation of TGN-lysosome vesicle to lysosome Show undefined attributes

catalystActivity	[CatalystActivity:10163998] GTPase activity of Dynamin [cytosol]
category	transition
compartment	[Compartment:263163] trans-Golgi network membrane [Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10164000
displayName	Translocation of TGN-lysosome vesicle to lysosome
eventOf	[Pathway:R-RNO-2132295] MHC class II antigen presentation - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-2213236] TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-2130641] Translocation of TGN-lysosome vesicle to lysosome - Homo sapiens
input	[Complex:R-RNO-2130552] AP-1 Clathrin coated nonameric complex [trans-Golgi network membrane] [SimpleEntity:R-ALL-29438] GTP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of TGN-lysosome vesicle to lysosome
output	[CandidateSet:R-RNO-2213185] Dynamin [cytosol] [SimpleEntity:R-ALL-29420] GDP [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol] [Complex:R-RNO-2213234] TGN-lysosome vesicle with nonameric complex [trans-Golgi network membrane]
precedingEvent	[BlackBoxEvent:R-RNO-2130619] TGN-lysosomal vesicle coat assembly - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2130641
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-2132295] MHC class II antigen presentation
(precedingEvent)	[Reaction:R-RNO-2213236] TGN-lysosome vesicle uncoating and release of nonameric complex to lysosome
(inferredTo)	[Reaction:R-HSA-2130641] Translocation of TGN-lysosome vesicle to lysosome

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