Reactome | Fibrillin C-terminal processing

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Fibrillin C-terminal processing Show undefined attributes

catalystActivity	[CatalystActivity:10163594] serine-type endopeptidase activity of FURIN [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10163596
displayName	Fibrillin C-terminal processing
eventOf	[Pathway:R-RNO-1566948] Elastic fibre formation - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Polymerisation:R-RNO-2129362] Fibrillin microfibril assembly - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-2129357] Fibrillin C-terminal processing - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-265402] Fbn1 [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Fibrillin C-terminal processing
output	[EntityWithAccessionedSequence:R-RNO-2159853] Fbn1 [extracellular region] [EntityWithAccessionedSequence:R-RNO-2159838] Fbn1 [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-2129357
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1566948] Elastic fibre formation
(precedingEvent)	[Polymerisation:R-RNO-2129362] Fibrillin microfibril assembly
(inferredTo)	[Reaction:R-HSA-2129357] Fibrillin C-terminal processing

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