Reactome | AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:10175717] protein serine/threonine kinase activity of AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-4416737] CTNNB1:AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-5229343] AXIN is phosphorylated in the destruction complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10122931
displayName	AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-RNO-1504189] Amer1 [cytosol] [EntityWithAccessionedSequence:R-RNO-5246690] Apc [cytosol] [EntityWithAccessionedSequence:R-RNO-195249] Axin1 [cytosol] [EntityWithAccessionedSequence:R-RNO-195263] CSNK1A1 [cytosol] [EntityWithAccessionedSequence:R-RNO-198619] Glycogen synthase kinase-3 beta [cytosol] [Complex:R-RNO-196206] PP2A [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-195250] AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol] - Homo sapiens
maxDepth	4
name	AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex
producedByEvent	[Reaction:R-RNO-195251] Assembly of the destruction complex - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-195250
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-RNO-5229343] AXIN is phosphorylated in the destruction complex
(physicalEntity)	[CatalystActivity:10175717] protein serine/threonine kinase activity of AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(output)	[Reaction:R-RNO-195251] Assembly of the destruction complex
(hasComponent)	[Complex:R-RNO-4416737] CTNNB1:AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]
(inferredTo)	[Complex:R-HSA-195250] AXIN:GSK3:CK1alpha:ub-APC:PP2A:AMER1 complex [cytosol]