Reactome | Translocation of p27 to the nucleoplasm

Schema > Reaction > Entries

Translocation of p27 to the nucleoplasm Show undefined attributes

category	transition
compartment	[Compartment:13231] nuclear envelope
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10120841
displayName	Translocation of p27 to the nucleoplasm
eventOf	[Pathway:R-RNO-69656] Cyclin A:Cdk2-associated events at S phase entry - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-187934] Inactivation of Cyclin A:Cdk2 complexes by p27/p21 - Rattus norvegicus [Reaction:R-RNO-69562] Inactivation of Cyclin E:Cdk2 complexes by p27/p21 - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-187506] Translocation of p27 to the nucleoplasm - Homo sapiens
input	[EntityWithAccessionedSequence:R-RNO-198622] Cdkn1b [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Translocation of p27 to the nucleoplasm
output	[EntityWithAccessionedSequence:R-RNO-182563] Cdkn1b [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-187506
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-69656] Cyclin A:Cdk2-associated events at S phase entry [Pathway:R-RNO-69202] Cyclin E associated events during G1/S transition
(precedingEvent)	[Reaction:R-RNO-187934] Inactivation of Cyclin A:Cdk2 complexes by p27/p21 [Reaction:R-RNO-69562] Inactivation of Cyclin E:Cdk2 complexes by p27/p21
(inferredTo)	[Reaction:R-HSA-187506] Translocation of p27 to the nucleoplasm