Reactome | phospho-MyrG-p-Y419-SRC [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

phospho-MyrG-p-Y419-SRC [plasma membrane] Show undefined attributes

candidateOf	[CandidateSet:R-RNO-5672734] RAF activating kinases [plasma membrane] - Rattus norvegicus
catalystActivities	[CatalystActivity:10221680] protein tyrosine kinase activity of MyrG-p-Y419-SRC [plasma membrane]
compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-RNO-8937795] MyrG-p-Y419-SRC:RUNX3 [plasma membrane] - Rattus norvegicus [Complex:R-RNO-377614] Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] - Rattus norvegicus [Complex:R-RNO-380768] PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-8937792] RUNX3 binds SRC - Rattus norvegicus [Reaction:R-RNO-8874083] p-Y397-PTK2 binds SRC - Rattus norvegicus [Reaction:R-RNO-9612219] ERBB4s80 binds to SRC - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10130003
displayName	phospho-MyrG-p-Y419-SRC [plasma membrane]
endCoordinate	536
hasModifiedResidue	[ModifiedResidue:9037058] N-myristoylglycine at 2 [ModifiedResidue:8937894] O4'-phospho-L-tyrosine at 419
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-1810408] MyrG-p-Y419-SRC [plasma membrane] - Homo sapiens
maxDepth	1
memberOf	[DefinedSet:R-RNO-9605569] MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] - Rattus norvegicus
name	phospho-MyrG-p-Y419-SRC Q9WUD9
negativelyRegulates	[NegativeRegulation:10203746] Negative regulation by 'MyrG-p-Y419-SRC [plasma membrane]'
producedByEvent	[Reaction:R-RNO-8937807] SRC phosphorylates RUNX3 - Rattus norvegicus
referenceEntity	[ReferenceGeneProduct:uniprot:Q9WUD9] UniProt:Q9WUD9 Src
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1810408
startCoordinate	2

Referrals

(hasComponent)	[Complex:R-RNO-377614] Integrin alphaIIb beta3:Active (p-Y419)-SRC [plasma membrane] [Complex:R-RNO-8937795] MyrG-p-Y419-SRC:RUNX3 [plasma membrane] [Complex:R-RNO-8874611] HGF:p-4Y-MET dimer:p-Y194,Y397,Y576,Y577-PTK2:MyrG-p-Y419-SRC [plasma membrane] [Complex:R-RNO-8874601] HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] [Complex:R-RNO-8874097] HGF:p-4Y-MET dimer:p-Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] [Complex:R-RNO-380768] PDGF:Phospho-PDGF receptor dimer:MyrG-p-Y419-SRC [plasma membrane] [Complex:R-RNO-9632399] Me260-ESR1:STRN:ESTG:MyrG-pY419 SRC:PI3K alpha [plasma membrane] [Complex:R-RNO-9603427] NTF3:p-5Y-NTRK3 homodimer:MyrG-p-Y419-SRC [plasma membrane] [Complex:R-RNO-9612227] ERBB4s80:MyrG-p-Y419-SRC [plasma membrane] [Complex:R-RNO-9021593] ESRs:STRN:ESTG:MyrG-pY419-SRC [plasma membrane]
(output)	[Reaction:R-RNO-8937807] SRC phosphorylates RUNX3
(activeUnit)	[CatalystActivity:10203741] protein tyrosine kinase activity of MyrG-p-Y419-SRC:RUNX3 [plasma membrane] [CatalystActivity:10202126] protein tyrosine kinase activity of HGF:p-4Y-MET dimer:p-Y194,Y397-PTK2:MyrG-p-Y419-SRC [plasma membrane] [CatalystActivity:10221680] protein tyrosine kinase activity of MyrG-p-Y419-SRC [plasma membrane] [CatalystActivity:10220591] protein tyrosine kinase activity of MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane]
(input)	[Reaction:R-RNO-8937792] RUNX3 binds SRC [Reaction:R-RNO-8874083] p-Y397-PTK2 binds SRC [Reaction:R-RNO-9612219] ERBB4s80 binds to SRC
(physicalEntity)	[CatalystActivity:10221680] protein tyrosine kinase activity of MyrG-p-Y419-SRC [plasma membrane]
(hasMember)	[DefinedSet:R-RNO-9605569] MyrG-p-Y419-SRC,MyrG-p-Y420-FYN [plasma membrane] [CandidateSet:R-RNO-1810413] p-Y419/420/426-N-myristoyl-SRC/FYN/YES1 [plasma membrane]
(regulator)	[NegativeRegulation:10203746] Negative regulation by 'MyrG-p-Y419-SRC [plasma membrane]'
(hasCandidate)	[CandidateSet:R-RNO-5672734] RAF activating kinases [plasma membrane]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-1810408] MyrG-p-Y419-SRC [plasma membrane]

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