Reactome | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

Schema > Pathway > Entries

Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins Show undefined attributes

created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10222961
displayName	Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
eventOf	[Pathway:R-RNO-174143] APC/C-mediated degradation of cell cycle proteins - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:161960] anaphase-promoting complex-dependent catabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-RNO-176412] Phosphorylation of the APC/C - Rattus norvegicus [Pathway:R-RNO-176409] APC/C:Cdc20 mediated degradation of mitotic proteins - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-176814] Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	5
name	Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-176814
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-174143] APC/C-mediated degradation of cell cycle proteins
(inferredTo)	[Pathway:R-HSA-176814] Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins

© 2026 Reactome

Cite Us!