Reactome | BTRC:CUL1:SKP1 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-RNO-174138] SCF-beta-TrCP:phospho-Emi1 complexes [cytosol] - Rattus norvegicus
consumedByEvent	[Reaction:R-RNO-174209] Phosphorylated Emi1 binds the beta-TrCP in the SCF complex - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10119086
displayName	BTRC:CUL1:SKP1 [cytosol]
hasComponent	[EntityWithAccessionedSequence:R-RNO-174237] Btrc [cytosol] [EntityWithAccessionedSequence:R-RNO-174230] Cul1 [cytosol] [EntityWithAccessionedSequence:R-RNO-174150] Skp1 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-174155] BTRC:CUL1:SKP1 [cytosol] - Homo sapiens
maxDepth	2
memberOf	[DefinedSet:R-RNO-1168601] (BTRC:CUL1:SKP1),(FBXW11:CUL1:SKP1) [cytosol] - Rattus norvegicus
name	BTRC:CUL1:SKP1
producedByEvent	[BlackBoxEvent:R-RNO-174203] SCF-mediated degradation of Emi1 - Rattus norvegicus
schemaClass	Complex
species	[Species:48895] Rattus norvegicus
stId	R-RNO-174155
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(output)	[BlackBoxEvent:R-RNO-174203] SCF-mediated degradation of Emi1
(activeUnit)	[CatalystActivity:10119105] ubiquitin-protein transferase activity of SCF-beta-TrCP:phospho-Emi1 complexes [cytosol]
(input)	[Reaction:R-RNO-174209] Phosphorylated Emi1 binds the beta-TrCP in the SCF complex
(hasMember)	[DefinedSet:R-RNO-1168601] (BTRC:CUL1:SKP1),(FBXW11:CUL1:SKP1) [cytosol]
(hasComponent)	[Complex:R-RNO-174138] SCF-beta-TrCP:phospho-Emi1 complexes [cytosol]
(inferredTo)	[Complex:R-HSA-174155] BTRC:CUL1:SKP1 [cytosol]