Reactome | Autodegradation of Cdh1 by Cdh1:APC/C

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Autodegradation of Cdh1 by Cdh1:APC/C Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10222949
displayName	Autodegradation of Cdh1 by Cdh1:APC/C
eventOf	[Pathway:R-RNO-174143] APC/C-mediated degradation of cell cycle proteins - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:161960] anaphase-promoting complex-dependent catabolic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-RNO-174057] Multiubiquitination of APC/C-associated Cdh1 - Rattus norvegicus [BlackBoxEvent:R-RNO-174058] Degradation of multiubiquitinated Cdh1 - Rattus norvegicus
inferredFrom	[Pathway:R-HSA-174084] Autodegradation of Cdh1 by Cdh1:APC/C - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	Autodegradation of Cdh1 by Cdh1:APC/C
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48895] Rattus norvegicus
stId	R-RNO-174084
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-174143] APC/C-mediated degradation of cell cycle proteins
(inferredTo)	[Pathway:R-HSA-174084] Autodegradation of Cdh1 by Cdh1:APC/C

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