Reactome | CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible)

Schema > Reaction > Entries

CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) Show undefined attributes

catalystActivity	[CatalystActivity:10155574] 1-acylglycerophosphocholine O-acyltransferase activity of TAZ [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10155576
displayName	CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible)
eventOf	[Pathway:R-RNO-1482798] Acyl chain remodeling of CL - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-1482759] MLCL is hydrolyzed to DLCL by PLA2G4A (IM) - Rattus norvegicus [Reaction:R-RNO-1482775] MLCL is acylated to CL by HADH (IM) - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-1482794] CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) - Homo sapiens
input	[SimpleEntity:R-ALL-1524079] 1-acyl LPC [mitochondrial inner membrane] [SimpleEntity:R-ALL-1524072] cardiolipin [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible)
output	[SimpleEntity:R-ALL-1498773] MLCL [mitochondrial inner membrane] [SimpleEntity:R-ALL-1524075] PC [mitochondrial inner membrane]
precedingEvent	[Reaction:R-RNO-1482781] MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) - Rattus norvegicus [Reaction:R-RNO-1482775] MLCL is acylated to CL by HADH (IM) - Rattus norvegicus [Reaction:R-RNO-1482850] MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) - Rattus norvegicus [Reaction:R-RNO-1483063] PG and CDP-DAG are converted to CL by CRLS1 - Rattus norvegicus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1482794
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-1482798] Acyl chain remodeling of CL
(precedingEvent)	[Reaction:R-RNO-1482759] MLCL is hydrolyzed to DLCL by PLA2G4A (IM) [Reaction:R-RNO-1482775] MLCL is acylated to CL by HADH (IM)
(inferredTo)	[Reaction:R-HSA-1482794] CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible)