Reactome | activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin

Schema > Reaction > Entries

activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:9979708] Wright, Adam, 2024-03-07
dbId	9990805
displayName	activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin
eventOf	[Pathway:R-RNO-140875] Common Pathway of Fibrin Clot Formation - Rattus norvegicus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-141040] Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-141046] activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin - Homo sapiens
input	[Complex:R-RNO-156786] activated thrombin (factor IIa) [extracellular region] [EntityWithAccessionedSequence:R-RNO-141030] Thbd [plasma membrane]
isInDisease	false
isInferred	true
name	activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin
output	[Complex:R-RNO-141038] activated thrombin:thrombomodulin [plasma membrane]
releaseDate	2024-03-27
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-141046
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-140875] Common Pathway of Fibrin Clot Formation
(precedingEvent)	[Reaction:R-RNO-141040] Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C
(inferredTo)	[Reaction:R-HSA-141046] activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin

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