Reactome | Phosphorylation of BIM by JNK

Schema > Reaction > Entries

Phosphorylation of BIM by JNK Show undefined attributes

catalystActivity	[CatalystActivity:10113390] protein serine/threonine kinase activity of MAPK8 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10113419
displayName	Phosphorylation of BIM by JNK
eventOf	[Pathway:R-RNO-111446] Activation of BIM and translocation to mitochondria - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-RNO-139919] Translocation of BIM to mitochondria - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-139918] Phosphorylation of BIM by JNK - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-RNO-140524] BIM sequestered to dynein (DLC1) [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation of BIM by JNK MAPK8 phosphorylates BCL2L11
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-RNO-140526] Dynein (DLC1) on microtubules [plasma membrane] [EntityWithAccessionedSequence:R-RNO-140525] phospho-Bcl2l11 [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-139918
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-111446] Activation of BIM and translocation to mitochondria
(precedingEvent)	[Reaction:R-RNO-139919] Translocation of BIM to mitochondria
(inferredTo)	[Reaction:R-HSA-139918] Phosphorylation of BIM by JNK

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