Reactome | Thrombin-activated PARs activate Gq

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Thrombin-activated PARs activate Gq Show undefined attributes

catalystActivity	[CatalystActivity:10112989] G protein-coupled receptor activity of Thrombin-activated PARs [plasma membrane]
category	transition
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10113024
displayName	Thrombin-activated PARs activate Gq
eventOf	[Pathway:R-RNO-456926] Thrombin signalling through proteinase activated receptors (PARs) - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-114558] Thrombin-activated PARs activate Gq - Homo sapiens
input	[SimpleEntity:R-ALL-29438] GTP [cytosol] [Complex:R-RNO-397803] Thrombin-activated PARs:Gq (inactive) [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Thrombin-activated PARs activate Gq Gq activation by PAR
output	[SimpleEntity:R-ALL-29420] GDP [cytosol] [Complex:R-RNO-397802] Thrombin-activated PAR:Gq (active) [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-114558
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-456926] Thrombin signalling through proteinase activated receptors (PARs)
(inferredTo)	[Reaction:R-HSA-114558] Thrombin-activated PARs activate Gq

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