Reactome | PNP catalyzes the conversion of guanine and (deoxy)ribose-1-phosphate to (deoxy)guanosine

Schema > Reaction > Entries

PNP catalyzes the conversion of guanine and (deoxy)ribose-1-phosphate to (deoxy)guanosine Show undefined attributes

catalystActivity	[CatalystActivity:10108220] purine-nucleoside phosphorylase activity of PNP trimer [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10112223
displayName	PNP catalyzes the conversion of guanine and (deoxy)ribose-1-phosphate to (deoxy)guanosine
eventOf	[Pathway:R-RNO-74217] Purine salvage - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-112034] PNP catalyzes the conversion of guanine and (deoxy)ribose-1-phosphate to (deoxy)guanosine - Homo sapiens
input	[SimpleEntity:R-ALL-83956] Gua [cytosol] [DefinedSet:R-ALL-500244] R1P, dRibP [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PNP catalyzes the conversion of guanine and (deoxy)ribose-1-phosphate to (deoxy)guanosine alpha-D-ribose 1-phosphate + guanine => guanosine + phosphate 2-deoxy-alpha-D-ribose 1-phosphate + guanine => 2'-deoxyguanosine + phosphate guanine + (deoxy)ribose 1-phosphate <=> (deoxy)guanosine + orthophosphate (NP)
output	[DefinedSet:R-ALL-500245] G, dG [cytosol] [SimpleEntity:R-ALL-29372] Pi [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-112034
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-74217] Purine salvage
(inferredTo)	[Reaction:R-HSA-112034] PNP catalyzes the conversion of guanine and (deoxy)ribose-1-phosphate to (deoxy)guanosine

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