PNP catalyzes the conversion of guanine and (deoxy)ribose-1-phosphate to (deoxy)guanosine

catalystActivity
catalystActivityReference [CatalystActivityReference:9643298] purine-nucleoside phosphorylase activity of NP trimer [cytosol] Characterization of purine nucleoside phosphorylase from human granulocytes and its metabolism of deoxyribonucleosides
category transition
compartment
created [InstanceEdit:112010] D'Eustachio, P, 2004-03-31 17:07:00
crossReference
dbId 112034
deleted
displayName PNP catalyzes the conversion of guanine and (deoxy)ribose-1-phosphate to (deoxy)guanosine
eventOf
input
isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name
  • PNP catalyzes the conversion of guanine and (deoxy)ribose-1-phosphate to (deoxy)guanosine
  • alpha-D-ribose 1-phosphate + guanine => guanosine + phosphate
  • 2-deoxy-alpha-D-ribose 1-phosphate + guanine => 2'-deoxyguanosine + phosphate
  • guanine + (deoxy)ribose 1-phosphate <=> (deoxy)guanosine + orthophosphate (NP)
orthologousEvent
output
releaseDate 2004-07-06
reverseReaction [Reaction:R-HSA-74249] PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose
reviewStatus [ReviewStatus:9821382] five stars
revised
schemaClass Reaction
species
stId R-HSA-112034
summation
updateTrackers
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