Reactome | NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP

Schema > Reaction > Entries

NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP Show undefined attributes

catalystActivity	[CatalystActivity:10110805] 5'-nucleotidase activity of NT5E:Zn2+ dimer [plasma membrane]
category	transition
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10110807
displayName	NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP
eventOf	[Pathway:R-RNO-74259] Purine catabolism - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-109278] NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP - Homo sapiens
input	[DefinedSet:R-ALL-500101] AMP, dAMP, GMP, IMP [extracellular region] [SimpleEntity:R-ALL-109276] H2O [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP AMP + H2O => adenosine + phosphate dAMP + H2O => 2'-deoxyadenosine + phosphate GMP + H2O => guanosine + phosphate IMP + H2O => inosine + phosphate
output	[DefinedSet:R-ALL-500104] Ade-Rib, dA, Gua-Rib, Ino [extracellular region] [SimpleEntity:R-ALL-109277] Pi [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-109278
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-74259] Purine catabolism
(inferredTo)	[Reaction:R-HSA-109278] NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP

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