Reactome | ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans

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ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans Show undefined attributes

catalystActivity	[CatalystActivity:10150904] beta-galactoside (CMP) alpha-2,3-sialyltransferase activity of ST3GAL4 [Golgi membrane]
category	transition
compartment	[Compartment:20699] Golgi membrane [Compartment:17963] Golgi lumen
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10150906
displayName	ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans
eventOf	[Pathway:R-RNO-975577] N-Glycan antennae elongation - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1022129] ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans - Homo sapiens
input	[SimpleEntity:R-ALL-975925] Neu5Ac [Golgi lumen] [SimpleEntity:R-ALL-975910] NGP [Golgi lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans Addition of alpha-2,3-sialic acid to N-glycan over a galactose by ST3GAL4
output	[OtherEntity:R-ALL-981615] Glycoprotein-Neu5Ac [Golgi lumen]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-1022129
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-975577] N-Glycan antennae elongation
(inferredTo)	[Reaction:R-HSA-1022129] ST3GAL4 transfers Neu5Ac to terminal Gal of N-glycans

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