Reactome | PGR binds PGR antagonists

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11126107
displayName	PGR binds PGR antagonists
eventOf	[Pathway:R-PFA-3371497] HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9726621] PGR binds PGR antagonists - Homo sapiens
input	[Complex:R-PFA-9725890] HSP90:ATP:FKBP4:PTGES3:PGR [cytosol] [DefinedSet:R-ALL-9726674] PGR antagonists [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	PGR binds PGR antagonists
output	[Complex:R-PFA-9726623] PGR:PGR antagonists [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-9726621
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-PFA-3371497] HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
(inferredTo)	[Reaction:R-HSA-9726621] PGR binds PGR antagonists