Reactome | TFIIH [nucleoplasm]

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TFIIH [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-PFA-5689862] Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] - Plasmodium falciparum [Complex:R-PFA-9684119] Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] - Plasmodium falciparum [Complex:R-PFA-6782116] Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] - Plasmodium falciparum [Complex:R-PFA-75890] pol II transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] - Plasmodium falciparum [Complex:R-PFA-6782230] TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] - Plasmodium falciparum [Complex:R-PFA-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] - Plasmodium falciparum [Complex:R-PFA-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] - Plasmodium falciparum
consumedByEvent	[Reaction:R-PFA-5691000] TFIIH binds GG-NER site to form a verification complex - Plasmodium falciparum [Reaction:R-PFA-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Plasmodium falciparum [BlackBoxEvent:R-PFA-6781818] RNA Pol II initiates transcription from damaged DNA template - Plasmodium falciparum
created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11110974
displayName	TFIIH [nucleoplasm]
hasComponent	[Complex:R-PFA-69221] CAK [nucleoplasm] [EntityWithAccessionedSequence:R-PFA-67443] ERCC2 [nucleoplasm] [EntityWithAccessionedSequence:R-PFA-67439] ERCC3 [nucleoplasm] [GenomeEncodedEntity:R-PFA-65912] Ghost homologue of GTF2H1 [nucleoplasm] [EntityWithAccessionedSequence:R-PFA-65914] GTF2H2 [nucleoplasm] [EntityWithAccessionedSequence:R-PFA-65916] GTF2H3 [nucleoplasm] [EntityWithAccessionedSequence:R-PFA-65918] GTF2H4 [nucleoplasm] [EntityWithAccessionedSequence:R-PFA-5688446] GTF2H5 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-109634] TFIIH [nucleoplasm] - Homo sapiens
maxDepth	3
name	TFIIH
producedByEvent	[Reaction:R-PFA-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Plasmodium falciparum
schemaClass	Complex
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-109634
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Referrals

(hasComponent)	[Complex:R-PFA-75890] pol II transcription complex containing 4-9 nucleotide long transcript [nucleoplasm] [Complex:R-PFA-6782230] TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] [Complex:R-PFA-6782220] TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] [Complex:R-PFA-6782222] TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] [Complex:R-PFA-6782219] TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] [Complex:R-PFA-6782205] TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] [Complex:R-PFA-6782116] Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] [Complex:R-PFA-9684119] Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] [Complex:R-PFA-6781861] Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] [Complex:R-PFA-6781822] Hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH [nucleoplasm] [Complex:R-PFA-6781821] Damaged dsDNA with open transcription bubble:Hyperphosphorylated RNA Pol II:TFIIH [nucleoplasm] [Complex:R-PFA-5689862] Ub:XPC:RAD23:CETN2:Distorted dsDNA:PAR-UV-DDB:TFIIH:PAR-PARP1,PAR-PARP2 [nucleoplasm] [Complex:R-PFA-75882] pol II transcription complex containing 9 nucleotide long transcript [nucleoplasm] [Complex:R-PFA-75902] pol II transcription complex containing 11 nucleotide long transcript [nucleoplasm] [Complex:R-PFA-157171] Pol II transcription complex containing extruded transcript to +30 [nucleoplasm] [Complex:R-PFA-157174] Pol II transcription complex with (ser5) phosphorylated CTD containing extruded transcript to +30 [nucleoplasm] [Complex:R-PFA-77053] RNA Pol II with phosphorylated CTD: CE complex [nucleoplasm] [Complex:R-PFA-77061] CE:Pol II CTD:Spt5 complex [nucleoplasm]
(output)	[Reaction:R-PFA-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein
(input)	[Reaction:R-PFA-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein [BlackBoxEvent:R-PFA-6781818] RNA Pol II initiates transcription from damaged DNA template [Reaction:R-PFA-5691000] TFIIH binds GG-NER site to form a verification complex
(inferredTo)	[Complex:R-HSA-109634] TFIIH [nucleoplasm]

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