Reactome | Apoptosis

Schema > Pathway > Entries

created	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
dbId	11128376
displayName	Apoptosis
eventOf	[TopLevelPathway:R-PFA-5357801] Programmed Cell Death - Plasmodium falciparum
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:2273] apoptotic process
hasDiagram	true
hasEHLD	false
hasEvent	[Pathway:R-PFA-109606] Intrinsic Pathway for Apoptosis - Plasmodium falciparum [Pathway:R-PFA-75153] Apoptotic execution phase - Plasmodium falciparum
inferredFrom	[Pathway:R-HSA-109581] Apoptosis - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	5
name	Apoptosis
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:170928] Plasmodium falciparum
stId	R-PFA-109581
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[TopLevelPathway:R-PFA-5357801] Programmed Cell Death
(hasEncapsulatedEvent)	[Pathway:R-PFA-166166] MyD88-independent TLR4 cascade [Pathway:R-PFA-5213460] RIPK1-mediated regulated necrosis [Pathway:R-PFA-168164] Toll Like Receptor 3 (TLR3) Cascade
(inferredTo)	[Pathway:R-HSA-109581] Apoptosis