Reactome | FOXO1,FOXO3:p-2S-SMAD2/3:SMAD4:Trim63 gene [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9625761] Orlic-Milacic, Marija, 2018-10-22
dbId	9625760
displayName	FOXO1,FOXO3:p-2S-SMAD2/3:SMAD4:Trim63 gene [nucleoplasm]
hasComponent	[DefinedSet:R-HSA-9614686] FOXO1,FOXO3 [nucleoplasm] [DefinedSet:R-HSA-173511] p-2S-SMAD2,3:SMAD4 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9625759] Trim63 gene [nucleoplasm]
inDisease	false
isChimeric	true
maxDepth	4
name	FOXO1,FOXO3:p-2S-SMAD2/3:SMAD4:Trim63 gene
positivelyRegulates	[PositiveGeneExpressionRegulation:9625781] Positive gene expression regulation by 'FOXO1,FOXO3:p-2S-SMAD2/3:SMAD4:Trim63 gene [nucleoplasm]'
producedByEvent	[Reaction:R-NUL-9625758] FOXO1,FOXO3 and SMAD3 bind Trim63 gene promoter - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stId	R-NUL-9625760
updateTrackers	[UpdateTracker:9902444] Update Tracker - [Complex:9625760] FOXO1,FOXO3:p-2S-SMAD2/3:SMAD4:Trim63 gene [nucleoplasm] - v78:[updateContainedComponent]

(updatedInstance)	[UpdateTracker:9902444] Update Tracker - [Complex:9625760] FOXO1,FOXO3:p-2S-SMAD2/3:SMAD4:Trim63 gene [nucleoplasm] - v78:[updateContainedComponent]
(regulator)	[PositiveGeneExpressionRegulation:9625781] Positive gene expression regulation by 'FOXO1,FOXO3:p-2S-SMAD2/3:SMAD4:Trim63 gene [nucleoplasm]'
(activeUnit)	[PositiveGeneExpressionRegulation:9625781] Positive gene expression regulation by 'FOXO1,FOXO3:p-2S-SMAD2/3:SMAD4:Trim63 gene [nucleoplasm]'
(output)	[Reaction:R-NUL-9625758] FOXO1,FOXO3 and SMAD3 bind Trim63 gene promoter

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