Reactome | NAB2 binds Egr1 at the Cdk5r1 promoter

Schema > Reaction > Entries

authored	[InstanceEdit:9658548] Rothfels, Karen, 2019-08-16
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9616372] Rothfels, Karen, 2018-08-10
dbId	9616362
displayName	NAB2 binds Egr1 at the Cdk5r1 promoter
edited	[InstanceEdit:9676974] Rothfels, Karen, 2020-02-24
input	[Complex:R-RNO-9616099] Cdk5r1 gene:Egr1 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-9612177] NAB2 [nucleoplasm]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9612004] ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	NAB2 binds Egr1 at the Cdk5r1 promoter
orthologousEvent	[Reaction:R-HSA-9616367] NAB2 binds EGR1 to repress CDK5R1 gene expression - Homo sapiens
output	[Complex:R-NUL-9616359] Cdk5r1 gene:Egr1:NAB2 [nucleoplasm]
releaseDate	2020-03-17
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9674653] Aletta, John M, 2020-01-17
schemaClass	Reaction
species	[Species:48887] Homo sapiens [Species:48895] Rattus norvegicus
stId	R-NUL-9616362
summation	[Summation:9616361] Cotransfection of human NAB2 and constitutively active Xenop...

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