Reactome | Ntrk2 promotes Tiam1 phosphorylation

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Ntrk2 promotes Tiam1 phosphorylation Show undefined attributes

authored	[InstanceEdit:9034391] Orlic-Milacic, Marija, 2018-01-05
catalystActivity	[CatalystActivity:9033336] protein tyrosine kinase activity of BDNF:p-5Y,S478-Ntrk2 homodimer:Tiam1 [plasma membrane]
category	omitted
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:9033334] Orlic-Milacic, Marija, 2017-12-20
dbId	9033333
displayName	Ntrk2 promotes Tiam1 phosphorylation
edited	[InstanceEdit:9037703] Orlic-Milacic, Marija, 2018-02-20
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-NUL-9033319] BDNF:p-5Y,S478-Ntrk2 homodimer:Tiam1 [plasma membrane]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9033267] TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Ntrk2 promotes Tiam1 phosphorylation
orthologousEvent	[BlackBoxEvent:R-HSA-9033284] NTRK2 promotes TIAM1 phosphorylation - Homo sapiens
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [Complex:R-NUL-9033335] BDNF:p-5Y,S478-Ntrk2 homodimer:p-Y829-Tiam1 [plasma membrane]
releaseDate	2018-03-21
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9037707] Antila, Hanna, 2018-02-13 [InstanceEdit:9037710] Castr�n, Eero, 2018-02-13
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stId	R-NUL-9033333
summation	[Summation:9033337] Mouse Ntrk2 (Trkb), activated by recombinant human BDNF, and...

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