Reactome | SYK binds p-Y15-Clec7a:1,3-beta-D-glucan

Schema > Reaction > Entries

authored	[InstanceEdit:5607752] Garapati, P V, 2014-07-14
category	binding
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:5607752] Garapati, P V, 2014-07-14
dbId	5607748
displayName	SYK binds p-Y15-Clec7a:1,3-beta-D-glucan
edited	[InstanceEdit:5607752] Garapati, P V, 2014-07-14
input	[EntityWithAccessionedSequence:R-MMU-5607650] p-Y15-Clec7a [plasma membrane] [EntityWithAccessionedSequence:R-HSA-58268] SYK [cytosol]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5607480] Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors [LiteratureReference:5607274] Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	SYK binds p-Y15-Clec7a:1,3-beta-D-glucan
orthologousEvent	[Reaction:R-HSA-5607738] SYK binds p-Y15-CLEC7A:1,3-beta-D-glucan - Homo sapiens
output	[Complex:R-NUL-5607692] p-Y15-Clec7a:SYK [plasma membrane]
releaseDate	2015-03-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5621625] Geijtenbeek, Teunis B H, 2014-09-02
schemaClass	Reaction
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stId	R-NUL-5607748
summation	[Summation:5607619] Spleen tyrosine kinase (SYK) is the key mediator of CLEC7A's...

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