Reactome | mouse Disp2 binds SHH N-terminal fragment

Schema > Reaction > Entries

authored	[InstanceEdit:5359176] Rothfels, Karen, 2014-04-08
category	binding
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:5362403] Rothfels, Karen, 2014-04-15
dbId	5362406
displayName	mouse Disp2 binds SHH N-terminal fragment
edited	[InstanceEdit:5364056] D'Eustachio, Peter, 2014-04-19
input	[EntityWithAccessionedSequence:R-HSA-5362407] CHOL-N-palmitoyl-L-cysteine-SHH(24-197) [plasma membrane] [EntityWithAccessionedSequence:R-MMU-5362351] Disp2 [plasma membrane]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:5358214] Dispatched and scube mediate the efficient secretion of the cholesterol-modified hedgehog ligand [LiteratureReference:5362320] Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	mouse Disp2 binds SHH N-terminal fragment
orthologousEvent	[Reaction:R-HSA-5362422] Hh-Np binds to DISP2 - Homo sapiens
output	[Complex:R-NUL-5362405] CHOL-N-palmitoyl-L-cysteine-SHH(24-197):Disp2 [plasma membrane]
releaseDate	2014-06-10
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5483156] Liu, Yulu Cherry, 2014-05-16
schemaClass	Reaction
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stId	R-NUL-5362406
summation	[Summation:5362404] Mouse Disp2 binds to human SHH as assessed by co-immunopreci...

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