Reactome | Clock acetylates histones H3, H4

Schema > Reaction > Entries

authored	[InstanceEdit:3214866] Jupe, S, 2013-03-12
catalystActivity	[CatalystActivity:4568935] histone acetyltransferase activity of Clock [cytosol]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:4568927] Jupe, S, 2013-09-19
dbId	4568946
displayName	Clock acetylates histones H3, H4
edited	[InstanceEdit:5146787] Jupe, S, 2013-11-18
input	[DefinedSet:R-HSA-4549252] Histone H3, H4 [nucleoplasm]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:3697912] Circadian regulator CLOCK is a histone acetyltransferase
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Clock acetylates histones H3, H4
orthologousEvent	[Reaction:R-HSA-3697920] CLOCK acetylates lysine-10 of histone H3, H4 - Homo sapiens [Reaction:R-HSA-5144542] CLOCK acetylates lysine-15 of histone H3, H4 - Homo sapiens
output	[DefinedSet:R-HSA-4568920] AcK10-histone H3, AcK-HIST1H4 [nucleoplasm]
releaseDate	2013-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5144557] Karagiannis, Tom, 2013-11-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stId	R-NUL-4568946
summation	[Summation:4568930] Clock is a central element of the core clock mechanism that ...
updateTrackers	[UpdateTracker:9984628] Update Tracker - [Reaction:4568946] Clock acetylates histones H3, H4 - v96:[modifyText]

(updatedInstance)

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