Reactome | CLOCK acetylates lysine-10 of histone H3, H4

Schema > Reaction > Entries

authored	[InstanceEdit:3214866] Jupe, S, 2013-03-12
catalystActivity	[CatalystActivity:4568936] histone acetyltransferase activity of CLOCK [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:3697937] Jupe, S, 2013-06-10
dbId	3697920
displayName	CLOCK acetylates lysine-10 of histone H3, H4
edited	[InstanceEdit:5146786] Jupe, S, 2013-11-18
eventOf	[Pathway:R-HSA-3214847] HATs acetylate histones - Homo sapiens
inferredFrom	[Reaction:R-NUL-4568946] Clock acetylates histones H3, H4 - Homo sapiens
input	[SimpleEntity:R-ALL-113560] Ac-CoA [nucleoplasm] [DefinedSet:R-HSA-4549252] Histone H3, H4 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	CLOCK acetylates lysine-10 of histone H3, H4
output	[DefinedSet:R-HSA-4568920] AcK10-histone H3, AcK-HIST1H4 [nucleoplasm] [SimpleEntity:R-ALL-2485002] CoA-SH [nucleoplasm]
releaseDate	2013-12-04
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:5144557] Karagiannis, Tom, 2013-11-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-3697920
summation	[Summation:3697909] CLOCK is a central element of the core clock mechanism that ...

(hasEvent)	[Pathway:R-HSA-3214847] HATs acetylate histones
(inferredTo)	[Reaction:R-NUL-4568946] Clock acetylates histones H3, H4

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