Reactome | p-NICD1:FBXW7:SKP1:CUL1:RBX1 [nucleoplasm]

Schema > Complex > Entries

catalystActivities	[CatalystActivity:2064880] ubiquitin-protein transferase activity of p-NICD1:FBXW7:SKP1:CUL1:RBX1 [nucleoplasm]
compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-NUL-2064883] FBXW7 mediates ubiquitination of phosphorylated NICD1 - Homo sapiens
created	[InstanceEdit:2064851] Orlic-Milacic, M, 2012-01-19
dbId	2064852
displayName	p-NICD1:FBXW7:SKP1:CUL1:RBX1 [nucleoplasm]
hasComponent	[Complex:R-HSA-1604469] FBXW7:SKP1:CUL1:RBX1 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-2064842] p-NICD1 [nucleoplasm]
inDisease	false
isChimeric	true
maxDepth	4
name	p-NICD1:FBXW7:SKP1:CUL1:RBX1
producedByEvent	[Reaction:R-NUL-2064853] FBXW7 binds phosphorylated NICD1 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens [Species:48892] Mus musculus
stId	R-NUL-2064852

(input)	[Reaction:R-NUL-2064883] FBXW7 mediates ubiquitination of phosphorylated NICD1
(physicalEntity)	[CatalystActivity:2064880] ubiquitin-protein transferase activity of p-NICD1:FBXW7:SKP1:CUL1:RBX1 [nucleoplasm]
(output)	[Reaction:R-NUL-2064853] FBXW7 binds phosphorylated NICD1

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