Reactome | PI is phosphorylated to PI5P by Pikfyve at the late endosome membrane

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PI is phosphorylated to PI5P by Pikfyve at the late endosome membrane Show undefined attributes

authored	[InstanceEdit:1678579] Williams, MG, 2011-10-18
catalystActivity	[CatalystActivity:1806267] 1-phosphatidylinositol-5-kinase activity of Pikfyve:VAC14:FIG4 [late endosome membrane]
category	transition
compartment	[Compartment:172574] late endosome membrane [Compartment:70101] cytosol
created	[InstanceEdit:1676083] Williams, MG, 2011-10-17
dbId	1676051
displayName	PI is phosphorylated to PI5P by Pikfyve at the late endosome membrane
edited	[InstanceEdit:1482514] Williams, MG, 2011-08-12
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-1806195] PI [late endosome membrane]
isChimeric	true
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:1675955] PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin [LiteratureReference:1460290] Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	PI is phosphorylated to PI5P by Pikfyve at the late endosome membrane
orthologousEvent	[Reaction:R-HSA-1675866] PI is phosphorylated to PI5P by PIKFYVE at the late endosome membrane - Homo sapiens
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-1806212] PI5P [late endosome membrane]
releaseDate	2012-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:2247963] Wakelam, Michael, 2012-05-14
schemaClass	Reaction
species	[Species:48892] Mus musculus [Species:48887] Homo sapiens
stId	R-NUL-1676051
summation	[Summation:1675906] At the late endosome membrane, the PAS complex, consisting o...

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