Reactome | Gata3 regulates the Il5 gene

Schema > BlackBoxEvent > Entries

Gata3 regulates the Il5 gene Show undefined attributes

authored	[InstanceEdit:9978120] May, Bruce, 2025-12-27
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:984] extracellular region
created	[InstanceEdit:9978109] May, Bruce, 2025-12-27
dbId	9978105
displayName	Gata3 regulates the Il5 gene
edited	[InstanceEdit:9978120] May, Bruce, 2025-12-27
input	[EntityWithAccessionedSequence:R-MMU-9978126] Il5 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9976372] Characterization of cis-regulatory elements and nuclear factors conferring Th2-specific expression of the IL-5 gene: a role for a GATA-binding protein [LiteratureReference:9976122] Genome-Wide Gene Expression Profiling Revealed a Critical Role for GATA3 in the Maintenance of the Th2 Cell Identity [LiteratureReference:9977460] Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene
maxDepth	1
modified	[InstanceEdit:9983731] May, Bruce, 2026-02-26
name	Gata3 regulates the Il5 gene
orthologousEvent	[BlackBoxEvent:R-HSA-9976371] GATA3 regulates expression of IL5 - Homo sapiens
output	[EntityWithAccessionedSequence:R-MMU-9978113] Il5 [extracellular region]
previousReviewStatus	[ReviewStatus:9821383] three stars
regulatedBy	[PositiveGeneExpressionRegulation:9978114] Positive gene expression regulation by 'Gata3:Il5 gene [nucleoplasm]'
releaseDate	2026-03-25
releaseStatus	NEW
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9983436] Barbutti, Isabella, 2026-02-24 [InstanceEdit:9983730] Lord, Graham M, 2026-02-26
schemaClass	BlackBoxEvent
species	[Species:48892] Mus musculus
stId	R-MMU-9978105
summation	[Summation:9978101] Gata3 bound to 3 sites in the promoter of the Il5 gene regul...

Cite Us!