Reactome | p-Y1007-Jak2 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-8950393] Il23r:p-Y-Jak2 [plasma membrane] - Mus musculus [Complex:R-MMU-1169241] Growth hormone:Tyrosine phosphorylated growth hormone receptor-Jak2 dimer:SHP2 [plasma membrane] - Mus musculus [Complex:R-MMU-1169241] Growth hormone:Tyrosine phosphorylated growth hormone receptor-Jak2 dimer:SHP2 [plasma membrane] - Mus musculus
consumedByEvent	[Reaction:R-MMU-877301] Dephosphorylation of Jaks by Ptps - Mus musculus
created	[InstanceEdit:997293] Garapati, P V, 2010-11-08
dbId	997296
displayName	p-Y1007-Jak2 [cytosol]
endCoordinate	1129
hasModifiedResidue	[ModifiedResidue:997291] O4'-phospho-L-tyrosine at 1007
inDisease	false
maxDepth	1
modified	[InstanceEdit:8949793] Jupe, Steve, 2016-11-29
name	p-Y1007-Jak2
referenceEntity	[ReferenceGeneProduct:uniprot:Q62120] UniProt:Q62120 Jak2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48892] Mus musculus
stId	R-MMU-997296
startCoordinate	1
updateTrackers	[UpdateTracker:9896792] Update Tracker - [EntityWithAccessionedSequence:997296] p-Y1007-Jak2 [cytosol] - v60:[modifyEndCoordinate, modifyName]

(updatedInstance)	[UpdateTracker:9896792] Update Tracker - [EntityWithAccessionedSequence:997296] p-Y1007-Jak2 [cytosol] - v60:[modifyEndCoordinate, modifyName]
(hasComponent)	[Complex:R-MMU-8950393] Il23r:p-Y-Jak2 [plasma membrane] [Complex:R-MMU-1169241] Growth hormone:Tyrosine phosphorylated growth hormone receptor-Jak2 dimer:SHP2 [plasma membrane] [Complex:R-MMU-1168908] Gh1:2x(p-Y341,Y346,Y498,Y545,Y577,Y639-Ghr):p-Y1007-Jak2 dimer [plasma membrane] [Complex:R-MMU-1169144] Growth hormone:Activated growth hormone receptor-p-Jak2 dimer [plasma membrane]
(activeUnit)	[CatalystActivity:1169196] non-membrane spanning protein tyrosine kinase activity of Growth hormone:Activated growth hormone receptor-p-Jak2 dimer:Stat1/Stat3 [plasma membrane] [CatalystActivity:2586556] protein tyrosine kinase activity of Lep:Lepr:p-Jak2 [plasma membrane]
(input)	[Reaction:R-MMU-877301] Dephosphorylation of Jaks by Ptps