Reactome | Tbx21 binds the Il12rb2 gene

Schema > Reaction > Entries

authored	[InstanceEdit:9943448] May, Bruce, 2025-03-28
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9943427] May, Bruce, 2025-03-29
dbId	9943435
displayName	Tbx21 binds the Il12rb2 gene
edited	[InstanceEdit:9943448] May, Bruce, 2025-03-28
input	[EntityWithAccessionedSequence:R-MMU-9943421] Il12rb2 gene [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9942501] Tbx21 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9942713] The transcription factor T-bet is induced by multiple pathways and prevents an endogenous Th2 cell program during Th1 cell responses
maxDepth	1
modified	[InstanceEdit:9962434] May, Bruce, 2025-08-05
name	Tbx21 binds the Il12rb2 gene
orthologousEvent	[Reaction:R-HSA-9942698] TBX21 binds the IL12RB2 gene - Homo sapiens
output	[Complex:R-MMU-9943426] Tbx21:Il12rb2 gene [nucleoplasm]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-09-18
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9962418] Barbutti, Isabella, 2025-08-04 [InstanceEdit:9962433] Lord, Graham M, 2025-08-05
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9943435
summation	[Summation:9943447] Tbx21 (T-bet) binds an intron of the Il12rb2 gene (Zhu et al...

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