Reactome | The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1

Schema > Reaction > Entries

The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10097090
displayName	The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1
eventOf	[Pathway:R-MMU-9930044] Nuclear RNA decay - Mus musculus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-MMU-9933575] MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome - Mus musculus
inferredFrom	[Reaction:R-HSA-9933559] The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1 - Homo sapiens
input	[Complex:R-MMU-9935798] CBCA:ZFC3H1:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9934098] PAPOLG [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9935784] Rbm26 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9935838] Rbm27 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-6791189] SKIV2L2 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9935812] YTHDC1 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9935827] YTHDC2 [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9933572] Zc3h3 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1
output	[Complex:R-MMU-9933554] PAXT:PAPOLG:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9933559
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-MMU-9930044] Nuclear RNA decay
(precedingEvent)	[Reaction:R-MMU-9933575] MTREX (MTR4, SKIV2L2) in PAXT:RBM26:RBM27:ZC3H3:YTHDC1:YTHDC2:CBCA:polyadenylated m7GpppN-RNA:PABPN1 binds the RNA exosome
(inferredTo)	[Reaction:R-HSA-9933559] The PAXT connection (ZFC3H1:MTREX, ZFC3H1:MTR4), RBM26, RBM27, PAPOLG, YTHDC1, and YTHDC2 bind CBCA:polyadenylated m7GpppN-RNA:PABPN1

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