Reactome | SPOP:CUL3:RBX1 [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-MMU-9929493] SPOP:CUL3:RBX1:CD274 [cytosol] - Mus musculus
consumedByEvent	[Reaction:R-MMU-9929484] SPOP:CUL3:RBX1 binds to CD274 - Mus musculus
created	[InstanceEdit:9984900] Weiser, Joel, 2026-03-16
dbId	10096575
displayName	SPOP:CUL3:RBX1 [cytosol]
hasComponent	2 × [EntityWithAccessionedSequence:R-MMU-975979] Cul3 [cytosol] 2 × [EntityWithAccessionedSequence:R-MMU-180582] RBX1 [cytosol] [Complex:R-MMU-9929379] SPOP dimer [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-9929377] SPOP:CUL3:RBX1 [cytosol] - Homo sapiens
maxDepth	3
name	SPOP:CUL3:RBX1
producedByEvent	[Reaction:R-MMU-9929486] SPOP-mediated degradation of CD274 by 26S Proteosome - Mus musculus
schemaClass	Complex
species	[Species:48892] Mus musculus
stId	R-MMU-9929377
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-MMU-9929484] SPOP:CUL3:RBX1 binds to CD274
(output)	[Reaction:R-MMU-9929486] SPOP-mediated degradation of CD274 by 26S Proteosome
(activeUnit)	[CatalystActivity:10096596] ubiquitin protein ligase activity of SPOP:CUL3:RBX1:CD274 [cytosol]
(hasComponent)	[Complex:R-MMU-9929493] SPOP:CUL3:RBX1:CD274 [cytosol]
(inferredTo)	[Complex:R-HSA-9929377] SPOP:CUL3:RBX1 [cytosol]

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