Reactome | p-S97-Bmal1:p-T451,T461-Clock and coactivators bind the Per3 gene

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p-S97-Bmal1:p-T451,T461-Clock and coactivators bind the Per3 gene Show undefined attributes

authored	[InstanceEdit:9909367] May, Bruce, 2024-05-11
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9909380] May, Bruce, 2024-05-13
dbId	9909388
displayName	p-S97-Bmal1:p-T451,T461-Clock and coactivators bind the Per3 gene
edited	[InstanceEdit:9909367] May, Bruce, 2024-05-11
input	[EntityWithAccessionedSequence:R-MMU-556795] Crebbp [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-5624510] Kmt2a [nucleoplasm] 3 × [Complex:R-MMU-9920708] p-S97-Bmal1:p-T451,T461-Clock [nucleoplasm] [EntityWithAccessionedSequence:R-MMU-9909372] Per3 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9909397] Genome-wide profiling of the core clock protein BMAL1 targets reveals a strict relationship with metabolism [LiteratureReference:5669331] Genome-wide and phase-specific DNA-binding rhythms of BMAL1 control circadian output functions in mouse liver [LiteratureReference:9929333] Transcriptional architecture and chromatin landscape of the core circadian clock in mammals [LiteratureReference:400229] A direct repeat of E-box-like elements is required for cell-autonomous circadian rhythm of clock genes
maxDepth	1
modified	[InstanceEdit:9938697] May, Bruce, 2025-02-18
name	p-S97-Bmal1:p-T451,T461-Clock and coactivators bind the Per3 gene
orthologousEvent	[Reaction:R-HSA-9909400] p-S90-BMAL1:p-T451,T461-CLOCK and coactivators bind the PER3 gene - Homo sapiens
output	[Complex:R-MMU-9909386] p-S97-Bmal1:p-T451,T461-Clock:Crebbp:Kmt2a:Per3 gene [nucleoplasm]
previousReviewStatus	[ReviewStatus:9821383] three stars
releaseDate	2025-03-26
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9938389] Sancar, Aziz, 2025-02-14 [InstanceEdit:9938694] Albrecht, Urs, 2025-02-18
schemaClass	Reaction
species	[Species:48892] Mus musculus
stId	R-MMU-9909388
summation	[Summation:9929274] A dimer of phosphorylated Bmal1:Clock heterodimers binds adj...

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